Effects of pollutant exposure on human health
|Lead Author||Arja, Rautio|
|Institution Contact||Faculty of Medicine, Arctic Health & Thule Institute University of Oulu PO Box 7300 FI-90014 University of Oulu Finland|
|Theme||Theme 4: Building Long-term Human Capacity|
|Session Name||4.4 Circumpolar Health and Well-Being|
|Datetime||Wed, Sep 14, 2016 10:30 AM - 10:45 AM|
|Abstract text||The incidence of many diseases has increased in the Arctic, and it has been assumed that pollutants may have a contributing effect especially in the heavily exposed populations. Investigations on the precise impact of environmental pollutants on human health are difficult to study, because there are many factors, which affect simultaneously and varying degrees. These include genetic background, age, sex, diseases, exposure history and environment. Environmental factors include mixtures of contaminants and other chemical compounds to which individuals are commonly exposed. Knowledge about the effects of mixtures is mainly missing and difficult to study at population level.
During the last twenty years the Arctic Monitoring and Assessment Programme (AMAP) has followed the levels of persistent organic pollutants (POPs) and toxic metals in human populations, especially pregnant women, and also in environment. Exposure during the fetal period is in special attention in the epidemiological and mechanistic (in vitro) studies, because fetal stage is the most vulnerable during human life. During the last decade there have been several research projects under the framework of the EU, which have focused on potential toxicity at low exposure levels of environmental contaminants to child development (like ENRICO, OBELIX, CLEAR, INUENDO, ArcRisk, PHIME) and in many of these projects also the Arctic population studies have been included. One goal of these research programs has been to collect all the existing evidence about the associations between environmental contaminants and measured health outcomes. The evaluation of potential health risks and their magnitude is needed.
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